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Beta 1, 3-D Glucan Works with the Immune System for Rapid Repair of Injuries

Over the last several decades, many researchers and clinicians have examined the effects of Beta-1, 3-D glucan on wound repair and other healing processes after injury even surgery. I offer an overview of how the immune system plays such a vital role in rapid recovery from these insults.

One will then realize the need to use Beta-1, 3-D glucan as part of your daily regimen. (Since we seldom plan ahead for accidents and injury.) The phagocytic phase of immune response begins within the first 2 to 6 hours after injury and proceeds for several days. Macrophages and other phagocytic cells are extremely active at the damage site. (A phagocyte is an immune cell that eats and disposes of the damaged tissue. He is the Pac-Man of the immune system.)

Evidence of injury comes form the increase in markers found in the blood following exercise, from the soreness in the muscles, and from direct examinations of samples of the damaged muscles. Studies demonstrate that some muscle fibers undergo degenerative changes following exercise. Macrophages and other phagocytic cells invade injured cells and adjacent tissues to accomplish the breakdown and removal of severely damages cells.The regenerative phase then restores the fiber to its normal condition. In the case of muscle fiber injury form exercise, the fibers adapt during this process so that future bouts of exercise of similar type, intensity, and duration cause less injury to the muscle. Repair of these fibers appears to be complete.

Researchers agree that macrophages are more ever-present than any other immune-derived cell associated with injury. Its role in injury repair is tissue remodeling and promotion of healing. Macrophage activities include removal of dead tissue and debris by eating up the old cells, chemical recycling, and the release of a wide spectrum of cellular cytokines (fax messages) to promote growth and regeneration properties. These activities positively affect the behavior of cells in the vicinity of the wound. Researchers have even explored the possible association of the "fax messages" with the ability of injured nerves to regenerate.

To achieve maximum health, an appropriate amount of exercise should be performed every day. For those that wish to have peak physical conditioning, a much higher level of exercise is necessary. Even without your immediate knowledge, tissue will become damaged and needs to be repaired. This process may be substantially enhanced by the daily use of Beta-1, 3-D glucan, through its proven effects to improve macrophage and other phagocytic cell functions.This author is convinced that the daily use of Beta-1, 3-D glucan will enhance overall immune function. In particular, I see it prudent to use the material regularly to improve the chance of rapid and complete repair of damage due to injury, regardless of whether the injury is accidental or planned.



[1] Mechanisms of exercise-induced muscle fiber injury. Armstrong RB; Warren GL; Warren JA Exercise Biochemistry Laboratory, University of Georgia, Athens. Sports Med, 1991 Sep, 12:3 184-207
[2] Initial events in exercise-induced muscular injury. Armstrong RB Department of Physical Education, University of Georgia, Athens 30602. Med Sci Sports Exerc, 1990 Aug, 22:4, 429-35
[3] Cross talk between the immune system and the nervous system in response to injury: implications for regeneration. Lotan M; Schwartz M Department of Neurobiology; Weizmann Institute of Science, Rehovot, Isreal. FASEB J, 1994 Oct, 8:13, 1026-33
[4] Mechanisms of exercise-induced delayed onset muscular soreness: a brief review. Armstrong RB Med Sci Sports Exerc, 1984 Dec, 16:6, 529-38
[5] Muscle damage and endurance events. Armstrong RB Sports Med, 1986 Sep-Oct, 3:5, 370-81

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